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The Pediatric Bone Marrow Transplant Program at St. Louis Children's Hospital, the first in Missouri created exclusively for children, has been in operation since 1991. The program provides both autologous (self) and allogeneic (related and unrelated) bone marrow transplants for lymphomas, leukemias, immunodeficiencies, metabolic disorders, and a variety of solid tumors. With patients ranging in age from infancy to adolescence, approximately two-thirds of the transplants to date have been allogeneic. One year survival rates are 70 percent for autologous and 60 percent for allogeneic, both of which exceed the national average.
St. Louis Children's Hospital performed its first allogeneic bone marrow transplant from parent to child in April 1991. In 1994, the National Marrow Donor Program approved the hospital as a center for matched unrelated bone marrow transplantation. The transplant program has since expanded into virtually every aspect of stem cell transplant medicine, offering treatments that utilize technologies including matched unrelated donors, peripheral stem cells, and umbilical cord blood.
Continuing to expand this unique transplant program, the hospital currently offers transplantation services for a variety of oncological and hematological illnesses, and has performed over 300 transplants. New protocols and coordination with other centers are being developed to offer this treatment modality for many other illnesses including sickle cell and autoimmune diseases